Mission :
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The Laboratory of Human Genetics of Infectious Diseases (Director: Dr Laurent Abel) at the Imagine Institute (Institut des Maladies Génétiques), Inserm (Institut National de la Santé et de la Recherche Médicale)/University Paris Descartes, Paris, France, is looking for motivated and qualified *PhD candidate/Post-Doc.* Our laboratory is working onthe genetic dissection of predisposition to infectious diseases. The lab comprised two teams working on genetic epidemiology and genetic immunology. The union of the two teams is highly synergic, facilitating an integrated approach to studies of the human genetics of infectious diseases. Our laboratory is also benefiting from the establishment of a sister laboratory at the Rockefeller University in New York in the framework of an INSERM-associated international laboratory of human genetics of infectious diseases. The Paris branch is now located within the new Imagine Institute dedicated to the study of genetic disorders, and offering cutting edge research and core facilities. Additional information about our laboratory is available at http://www.hgid.net/, and about our Institute is available at http://www.institutimagine.org/en/. Selected candidates will be involved in projects on the genetic background of common human infectious diseases, especially due to mycobacterial (e.g. tuberculosis, leprosy), and viral (e.g. hepatitis B and C virus, herpes virus) agents. These projects encompass the entire spectrum of modern genetic epidemiology reaching from familial analyses and genome-wide association studies to next-generation-sequencing (whole exome and genome sequencing) and other high-throughput data (genomics, transcriptomics). Accordingly, you will apply and develop genetic epidemiological and/or bioinformatic methods and cooperate with international groups. For the post-doctoral position, previous experience with the analysis of large genomic datasets, such as genome-wide and next-generation sequencing studies is required. Knowledge in epigenetics (e.g. methylation studies) would also be appreciated.
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